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GLP-1RA increased the abundance of AKK, while Akk11 supplementation further amplifies the GLP-1-related signal, forming a positive feedback loop
Environmental factors such as temperature fluctuations and light exposure can accelerate these processes
Early-life adversity may be particularly relevant because it can produce long-lasting alterations in stress responsivity and physiological homeostasis across the lifespan (Smith and Pollak, 2020)
EGT can reduce the damage to hippocampal neurons induced by D-galactose and improve the learning and memory ability of mice by regulating the AMPK/SIRT1/PGC-1 pathway
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