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All analyses were operated in data-dependent mode, where the most intense peptides were automatically selected for fragmentation by high-energy collision-induced dissociation

Box 1: Recent Trump Administration Obesity Drug Initiatives In November 2025, the Trump administration announced reaching a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1s for Medicare, Medicaid, and those purchasing the drugs directly from the manufacturers through a new TrumpRx website

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