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Vilsbll T, Krarup T, Sonne J, Madsbad S, Vlund A, Juul AG, et al

Strategies for breaking through Dose adjustment is the most direct pharmacological approach

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The following adverse reactions are discussed elsewhere: Hyperglycemia or Hypoglycemia with Changes in Insulin Regimen [see Warnings and Precautions (5.2)] Hypoglycemia [seeWarnings and Precautions (5.3)] Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in clinical trials of a drug cannot be directly compared to rates in the clinical trial of another drug and may not reflect the rates observed in practice