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Further information was retrieved from the American Diabetes Association (ADA), Clinicaltrials.gov and clinicaltrials.eu websites

N Engl J Med, Online ahead of print, doi: 10.1056/NEJMoa2416394

The vermilion tissue medial to this triangular marking is used to augment the deficient vermilion underneath the cupid's bow

Reusing needles: This practice increases infection risk, causes needle blunting (leading to more painful injections), and may introduce air bubbles or contamination