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It does this by: Stimulating your pancreas to release insulin (which lowers blood sugar) Slowing down how fast your stomach empties (so you feel full longer) Reducing the release of another hormone called glucagon (which raises blood sugar) Acting on the brain to decrease appetite In people with type 2 diabetes or metabolic challenges, the body either doesnt make enough GLP-1 or doesnt respond to it properly

This shift was recapitulated in female Bbs5 / mice (Supplemental Figure 2, BD)

CrossRef Prostaglandin D2 enhances lipid accumulation through suppression of lipolysis via DP2 (CRTH2) receptors in adipocytes Eri Wakai, Kosuke Aritake, Yoshihiro Urade, Ko Fujimori Biochemical and Biophysical Research Communications.2017

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