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A peer-reviewed overview in the International Journal of Molecular Sciences (Araj et al., Medical University of Warsaw, 2025) establishing Epithalon as a highly bioactive pineal tetrapeptide with documented mechanisms spanning telomere maintenance, epigenetic regulation, antioxidant defense, immune recalibration, and circadian rhythm restoration provides the scientific framework for all five mechanisms described in this section

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In addition to SOD-mimetic compounds, Salen-based organic compounds, possessing hydrogen peroxide scavenging activity have been prepared and tested as Glutathione peroxidase mimetics